Board Thread:New on 3-bromopyruvate Wikia/@comment-26400607-20150528164629/@comment-69.158.18.25-20160114021709

Thank you very much for posting!

Our thread on Cancer Compass has been talking about using a spectrophotometer to measure 3-BP purity. From a chemist's perspective does this idea make sense? A spectro would be within the budget and competency of non-chemists.

There are a whole bunch of interesting chemicals that a little bit of chemical background could help unlock for people. Many of these reformulations would be safer and more effective forms. The cyclo-dextrin 3-BP formalation looks quite promising. The instructions for synthesis looks quite simple, one of the only holdbacks from doing some kitchen chemistry was the sonicator. (The Mit-3BP looks somewhat scary to me. It is not obvious that such a formulation would be safe in vivo. The    3-BP would get dragged to the mitochondria, though if this were a healthy cell that might not be a good thing.)

https://docs.google.com/viewer?url=patentimages.storage.googleapis.com/pdfs/US20060058383.pdf

http://www.ncbi.nlm.nih.gov/pubmed/25709804 http://www.ncbi.nlm.nih.gov/pubmed/25326230http://www.ncbi.nlm.nih.gov/pubmed/25999714